SCHEMBL4138642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL946948	0.91	HTT (0.75)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL4140825	0.89	HTT (0.68)	HTTALOX15POLBUSP2PTPN7
	Hydrochloric Acid SCHEMBL946927	0.89	HTT (0.72)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL17482177	0.88	HTT (0.56)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL27930399	0.87	HTT (0.59)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL948912	0.87	HTT (0.59)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL3712068	0.85	RAB9A (0.67)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL21144202	0.85	HTT (0.68)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL1936057	0.85	HTT (0.86)	HTTALOX15POLBUSP2PTPN7
	SCHEMBL12767148	0.85	HTT (0.83)	HTTALOX15POLBUSP2PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.