Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.52 |
| ▸ | KIT | P10721 | 2/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646043 | 1.00 | KDR (0.53) | KDRPDGFRAKITCSF1RPIK3CD | |
| SCHEMBL28423297 | 0.88 | PDGFRA (0.52) | KDRPDGFRAKIT | |
| SCHEMBL30646064 | 0.88 | PDGFRA (0.52) | KDRPDGFRAKIT | |
| SCHEMBL28421305 | 0.88 | PIK3CD (0.54) | KDRPDGFRAKITCSF1RPIK3CD | |
| SCHEMBL29111054 | 0.83 | ACHE (0.51) | KDRPDGFRAKITCSF1RPIK3CD | |
| SCHEMBL30646030 | 0.83 | ACHE (0.51) | KDRPDGFRAKITCSF1RPIK3CD | |
| SCHEMBL29111070 | 0.81 | SOS1 (0.39) | PDGFRAEGFRERBB2 | |
| SCHEMBL30646035 | 0.78 | EGFR (0.61) | PIK3CDPIK3CAPIK3CBPIK3CGEGFR | |
| SCHEMBL14489848 | 0.75 | ACHE (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGEGFR | |
| SCHEMBL1401697 | 0.75 | PIK3CD (0.51) | KDRPDGFRAKITCSF1RPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |