Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015600 | 0.80 | EGFR (0.63) | EGFR | |
| SCHEMBL4798188 | 0.79 | EGFR (0.78) | EGFRERBB2 | |
| SCHEMBL4798180 | 0.79 | EGFR (0.78) | EGFRERBB2 | |
| SCHEMBL14489848 | 0.79 | ACHE (0.57) | EGFRERBB2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30646043 | 0.78 | KDR (0.53) | EGFRERBB2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL28433303 | 0.78 | KDR (0.53) | EGFRERBB2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL28421305 | 0.78 | PIK3CD (0.54) | EGFRERBB2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29111054 | 0.77 | ACHE (0.51) | EGFRERBB2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30646030 | 0.77 | ACHE (0.51) | EGFRERBB2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29623598 | 0.76 | EGFR (0.69) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |