SCHEMBL28433595

SCHEMBL28433595

O=Cc1[nH]c(Cl)c(C=O)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13488597 0.76 SMN1; SMN2 (0.36) MEN1ALDH1A1KMT2ATDP1
SCHEMBL18721951 0.76 MEN1 (0.30) MEN1ALDH1A1KMT2ATDP1
SCHEMBL13488605 0.76 TYMP (0.31) MEN1ALDH1A1KMT2ATDP1
SCHEMBL29952691 0.75
SCHEMBL1808770 0.65 MEN1 (0.45) MEN1ALDH1A1KMT2ATDP1
SCHEMBL21643711 0.65 MEN1 (0.45) MEN1ALDH1A1KMT2ATDP1
SCHEMBL13064760 0.62 ALDH1A1 (0.43) MEN1ALDH1A1KMT2ATDP1
SCHEMBL4658299 0.62 ALDH1A1 (0.43) MEN1ALDH1A1KMT2ATDP1
SCHEMBL29870960 0.60 SMN1; SMN2 (0.42) MEN1ALDH1A1KMT2ATDP1
SCHEMBL1811779 0.60 ALDH1A1 (0.41) MEN1ALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100474-B Synthetic method of cyanine dye and application of cyanine dye as acid-base response fluorescent reagent 三峡大学 2021-03-23 CN claimed
CN-111100474-A Synthetic method of cyanine dye and application of cyanine dye as acid-base response fluorescent reagent 三峡大学 2020-05-05 CN claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-111100474-B Synthetic method of cyanine dye and application of cyanine dye as acid-base response fluorescent reagent 三峡大学 2021-03-23 CN disclosed
CN-111100474-A Synthetic method of cyanine dye and application of cyanine dye as acid-base response fluorescent reagent 三峡大学 2020-05-05 CN disclosed