Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10331727 | 0.82 | FNTA (0.48) | KMT2AERN1ALDH1A1HPGDTLR2 | |
| SCHEMBL1014909 | 0.82 | HSD17B10 (0.39) | KMT2AMEN1ERN1ALDH1A1HPGD | |
| Water SCHEMBL6002780 | 0.81 | HSD17B10 (0.38) | KMT2AMEN1ERN1ALDH1A1HPGD | |
| SCHEMBL28426811 | 0.81 | ABCG2 (0.46) | KMT2AMEN1ERN1ALDH1A1HTT | |
| SCHEMBL28554216 | 0.81 | MEN1 (0.53) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL140239 | 0.77 | GAA (0.50) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29463214 | 0.77 | GAA (0.50) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL743608 | 0.76 | ALDH1A1 (0.57) | KMT2AMEN1ERN1ALDH1A1HPGD | |
| SCHEMBL28923677 | 0.76 | ERN1 (0.41) | KMT2AMEN1ERN1ALDH1A1HPGD | |
| SCHEMBL16724689 | 0.76 | ERN1 (0.41) | KMT2AMEN1ERN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111454200-A | Compounds and their use for modulating hemoglobin | 全球血液疗法股份有限公司 | 2020-07-28 | — | — | CN | disclosed |