Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743608 | 0.80 | ALDH1A1 (0.57) | ERN1CA1CA2TLR2TLR1 | |
| SCHEMBL16724689 | 0.80 | ERN1 (0.41) | ERN1CA1CA2TLR2TLR1 | |
| SCHEMBL16732140 | 0.80 | ERN1 (0.41) | ERN1CA1CA2TLR2TLR1 | |
| SCHEMBL311198 | 0.78 | ERN1 (0.54) | ERN1CA1CA2TRIM24TRIM33 | |
| SCHEMBL1014909 | 0.76 | HSD17B10 (0.39) | ERN1CA1CA2TLR2TLR1 | |
| SCHEMBL14354200 | 0.76 | MAOA (0.43) | ERN1CA1CA2TLR2TLR1 | |
| SCHEMBL11440275 | 0.76 | LMNA (0.55) | ERN1ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL19738122 | 0.76 | SRC (0.56) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL3551620 | 0.76 | ALDH1A1 (0.51) | ERN1CA1CA2TLR2TLR1 | |
| SCHEMBL28434065 | 0.76 | KMT2A (0.41) | ERN1CA1CA2TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316568-A | 2-formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-113316568-A | 2-formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2021-08-27 | — | — | CN | disclosed |