SCHEMBL743608

SCHEMBL743608

COc1cccc(O)c1C=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
MAPT P10636 3/20 0.57
TP53 P04637 2/20 0.57
KDM4E B2RXH2 2/20 0.57
MAPK1 P28482 2/20 0.57
HPGD P15428 2/20 0.57
LMNA P02545 1/20 0.57
CYP3A4 P08684 1/20 0.57
ALOX15 P16050 1/20 0.57
ALOX12 P18054 1/20 0.57
HSD17B10 Q99714 1/20 0.57
ERN1 O75460 4/20 0.56
TLR2 O60603 1/20 0.56
TLR1 Q15399 1/20 0.56
TLR6 Q9Y2C9 1/20 0.56
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
TSHR P16473 1/20 0.54
BACE1 P56817 2/20 0.48
APP P05067 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170690 0.85 ERN1 (0.55) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL28870795 0.82 XDH (0.53) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL28870792 0.82 XDH (0.53) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL28857462 0.82 MAPT (0.59) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL27685686 0.81 ERN1 (0.52) ALDH1A1MAPTTP53KDM4EMAPK1
Bromomethane SCHEMBL28079811 0.81 ERN1 (0.52) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL10922927 0.80 BACE1 (0.52) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL15349839 0.80 LMNA (0.47) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL9598490 0.80 ERN1 (0.41) ALDH1A1MAPTTP53KDM4EMAPK1
SCHEMBL3828263 0.80 MAPT (0.57) ALDH1A1MAPTTP53KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP claimed
CN-117327744-A Method for synthesizing aromatic alcohol by catalyzing aromatic aldehyde by using wild bacillus and application of method 常州大学 2024-01-02 CN claimed
CN-114478219-B Synthetic method of natural product with broad-spectrum antibacterial activity 遵义医科大学 2023-12-12 CN claimed
WO-2023195794-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS 한국화학연구원 2023-10-12 WO claimed
CN-114478219-A Separation and synthesis method of natural product with broad-spectrum antibacterial activity 遵义医科大学 2022-05-13 CN claimed
CN-106674356-A Preparation method of fire retardants containing fiber-based phosphatidic acid 宣城市聚源精细化工有限公司 2017-05-17 CN claimed
CN-104892556-B One class stilbene coumarin derivatives and preparation method thereof and purposes 合肥工业大学 2017-01-04 CN claimed
CN-101768065-B Method for preparing 6-dimethoxysalicylaldehyde CHENGDU CHEMPARTNER CO LTD 2014-01-29 CN claimed
JP-4587669-B2 2010-11-24 JP claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
JP-2005509662-A 2005-04-14 JP claimed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 CN claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 EP claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 ALDH1A1 7/4885MAPT 777/4885TP53 891/4885
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 ALDH1A1 83/4885MAPT 685/4885TP53 4109/4885
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS FGB, NR4A1, CYP2E1 ALDH1A1 105/4885MAPT 3110/4885TP53 3755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.