Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28426049 | 0.88 | KMT2A (0.43) | GAASMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL28430288 | 0.85 | ADORA3 (0.41) | SMN1; SMN2MAPTLMNATSHRMAPK1 | |
| SCHEMBL28428820 | 0.84 | PADI4 (0.45) | GAASMN1; SMN2LMNAAHRALDH1A1 | |
| SCHEMBL28430717 | 0.82 | POLB (0.46) | SMN1; SMN2MAPTLMNAMAPK1NPC1 | |
| SCHEMBL28431825 | 0.76 | SMN1; SMN2 (0.46) | MAPK14GAASMN1; SMN2MAPTLMNA | |
| SCHEMBL28438083 | 0.72 | RAB9A (0.59) | GAASMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL4203809 | 0.70 | MEN1 (0.61) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL28428727 | 0.68 | ADORA3 (0.42) | MAPK14SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL4200653 | 0.68 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTLMNATSHRALDH1A1 | |
| SCHEMBL24864974 | 0.65 | KMT2A (0.66) | GAASMN1; SMN2MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108148064-B | Method for preparing pyrazole quinoxalinone derivative | 浙江百斯特化工有限公司 | 2020-06-26 | — | — | CN | disclosed |