Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2840152 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP1A2CYP2C19RAB9ATDP1 | |
| SCHEMBL2846951 | 0.94 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP2C19RAB9ATDP1 | |
| SCHEMBL1694984 | 0.90 | RAB9A (0.62) | SMN1; SMN2CYP1A2RAB9ATDP1LMNA | |
| Hydrochloric Acid SCHEMBL7603529 | 0.88 | RAB9A (0.61) | SMN1; SMN2CYP1A2RAB9ATDP1LMNA | |
| SCHEMBL3775207 | 0.86 | RAB9A (0.63) | SMN1; SMN2CYP1A2CYP2C19RAB9ALMNA | |
| SCHEMBL14562256 | 0.85 | MTNR1A (0.58) | SMN1; SMN2CYP1A2CYP2C19RAB9ATDP1 | |
| Fumaric Acid SCHEMBL7602759 | 0.83 | KMT2A (0.62) | SMN1; SMN2RAB9ATDP1LMNAHRH3 | |
| SCHEMBL7601765 | 0.83 | LMNA (0.70) | SMN1; SMN2RAB9ATDP1LMNAALOX15 | |
| Maleic Acid SCHEMBL7602749 | 0.83 | KMT2A (0.62) | SMN1; SMN2RAB9ATDP1LMNAHRH3 | |
| SCHEMBL18381340 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP1A2CYP2C19RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251324-A1 | HETEROARYL-ALKYLCARBAMATE COMPOUNDS AND THEIR USE AS INHIBITORS OF THE FAAH ENZYME | Sanofi-Aventis (FR) | 2010-11-17 | — | — | EP | disclosed |
| EP-1720829-B1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-10-14 | — | — | EP | disclosed |