Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032035 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL16574882 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| Acrylamide SCHEMBL25206068 | 0.82 | ALOX15 (0.41) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL730168 | 0.81 | HSD17B10 (0.54) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL2733785 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| Bicarbonate SCHEMBL16668577 | 0.76 | ALOX15 (0.50) | ALDH1A1TDP1HSD17B10MEN1KMT2A | |
| SCHEMBL16574887 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| Formaldehyde SCHEMBL7056596 | 0.76 | ALOX15 (0.55) | HSD17B10MEN1KMT2AALOX15ANPEP | |
| SCHEMBL15032034 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1TDP1HSD17B10 | |
| Carbamic Acid SCHEMBL10977422 | 0.75 | ALOX15 (0.48) | ALDH1A1TDP1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491982-B | Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods related thereto | 北卡罗来纳大学查佩尔希尔分校 | 2023-04-18 | — | — | CN | disclosed |
| CN-111491982-A | Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods related thereto | 北卡罗来纳大学查佩尔希尔分校 | 2020-08-04 | — | — | CN | disclosed |