Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16574878 | 0.98 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRMAPK1MEN1 | |
| SCHEMBL15032035 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRMAPK1MEN1 | |
| SCHEMBL16574882 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRMAPK1MEN1 | |
| SCHEMBL16574887 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRMAPK1MEN1 | |
| SCHEMBL15032039 | 0.76 | HSD17B10 (0.46) | MEN1KMT2AITGB3ITGA2BCHRM5 | |
| SCHEMBL28434860 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRMAPK1MEN1 | |
| SCHEMBL6530019 | 0.72 | TSHR (0.42) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL730168 | 0.72 | HSD17B10 (0.54) | ALDH1A1TDP1TSHRMAPK1MEN1 | |
| SCHEMBL22743444 | 0.72 | HRH2 (0.42) | ALDH1A1TDP1MEN1KMT2AITGB3 | |
| SCHEMBL16574879 | 0.69 | ITGB3 (0.44) | ALDH1A1MAPK1MEN1KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013086523-A2 | INJECTABLE HYDROGELS | WILLIAM MARSH RICE UNIVERSITY (US) | 2013-06-13 | — | — | WO | disclosed |