Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434991 | 0.82 | RAB9A (0.52) | NPC1HPGDRAB9AMAPTLMNA | |
| SCHEMBL28519236 | 0.77 | MEN1 (0.49) | HPGDLMNAGAAL3MBTL1KMT2A | |
| SCHEMBL3893770 | 0.76 | MEN1 (0.55) | MAPTGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL28519668 | 0.76 | TSHR (0.50) | HPGDGAAKMT2AMEN1KDM4E | |
| SCHEMBL28895673 | 0.74 | GAA (0.55) | GAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL2791916 | 0.73 | NPC1 (0.63) | NPC1HPGDRAB9AMAPTLMNA | |
| SCHEMBL16398364 | 0.72 | RAB9A (1.00) | NPC1HPGDRAB9AMAPTLMNA | |
| SCHEMBL2773681 | 0.72 | MAPT (0.52) | NPC1HPGDRAB9AMAPTLMNA | |
| SCHEMBL866784 | 0.72 | GSK3B (0.61) | NPC1HPGDRAB9AMAPTLMNA | |
| SCHEMBL28895513 | 0.71 | HPGD (0.56) | NPC1HPGDRAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096329-B | β -hydroxy phosphate and asymmetric synthesis method thereof | 三峡大学 | 2020-06-30 | — | — | CN | disclosed |