Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Glycolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 3/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | CBS | P35520 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL508095 | 0.97 | — | — | |
| Pimagedine SCHEMBL27357177 | 0.83 | LMNA (0.43) | CYP2C19OR51E2GLRA1SLC6A9ACHE | |
| Glycolic Acid SCHEMBL3643774 | 0.82 | — | — | |
| Glycolic Acid SCHEMBL27867705 | 0.82 | — | — | |
| Glycolic Acid SCHEMBL3232528 | 0.82 | — | — | |
| Glycolic Acid SCHEMBL1373369 | 0.82 | — | — | |
| Malonic Acid SCHEMBL28390067 | 0.80 | LDHA (0.60) | CYP2C19OR51E2GLRA1SLC6A9ACHE | |
| Pimagedine SCHEMBL507996 | 0.79 | KDM4E (0.40) | CYP2C19OR51E2GLRA1SLC6A9ACHE | |
| Glycolic Acid SCHEMBL5551718 | 0.78 | — | — | |
| Glycolic Acid SCHEMBL9178990 | 0.78 | OR51E2 (0.44) | CYP2C19OR51E2GLRA1SLC6A9THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111394579-B | Extraction method of rare earth element, eutectic solvent and preparation method thereof | 浙江大学 | 2021-06-22 | — | — | CN | claimed |
| CN-111394579-A | Extraction method of rare earth element, eutectic solvent and preparation method thereof | 浙江大学 | 2020-07-10 | — | — | CN | claimed |
| CN-111394579-B | Extraction method of rare earth element, eutectic solvent and preparation method thereof | 浙江大学 | 2021-06-22 | — | — | CN | disclosed |
| CN-111394579-A | Extraction method of rare earth element, eutectic solvent and preparation method thereof | 浙江大学 | 2020-07-10 | — | — | CN | disclosed |