Pimagedine

Pimagedine

SCHEMBL507996

N=C(N)NN.O=C(O)CO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
KDM5C P41229 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
CYP1A2 P05177 1/20 0.40
TSHR P16473 1/20 0.40
NFKB1 P19838 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
THPO P40225 1/20 0.40
CYP2C19 P33261 1/20 0.39
LMNA P02545 1/20 0.38
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
OR51E2 Q9H255 2/20 0.33
GLRA1 P23415 1/20 0.33
SLC6A9 P48067 1/20 0.33
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pimagedine SCHEMBL27357177 0.97 LMNA (0.43) KDM4EKDM5CPHF8KDM2ACYP1A2
Malonic Acid SCHEMBL508810 0.86 LDHA (0.53) KDM4EKDM5CPHF8KDM2ACYP1A2
Succinic Acid SCHEMBL28239345 0.83 KDM4E (0.59) KDM4EKDM5CPHF8KDM2ACYP1A2
Succinic Acid SCHEMBL30862138 0.83 KDM4E (0.59) KDM4EKDM5CPHF8KDM2ACYP1A2
Malonic Acid SCHEMBL508612 0.83 LDHA (0.50) KDM4EKDM5CPHF8KDM2ACYP1A2
Malonic Acid SCHEMBL508611 0.83 LDHA (0.50) KDM4EKDM5CPHF8KDM2ACYP1A2
Pimagedine SCHEMBL27540257 0.82 KDM4E (0.46) KDM4EKDM5CPHF8KDM2ACYP1A2
Pimagedine SCHEMBL6665719 0.82 TSHR (0.50) KDM4EKDM5CPHF8KDM2ACYP1A2
Glycolic Acid SCHEMBL508095 0.82
Pimagedine SCHEMBL9952232 0.82 TSHR (0.50) KDM4EKDM5CPHF8KDM2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8425702-B2 Precursor of an explosive composition including at least one ionic liquid and a method of desensitizing an explosive composition ALLIANT TECHSYSTEMS INC. (US) 2013-04-23 US claimed
US-20120024437-A1 PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION ALLIANT TECHSYSTEMS INC. (US) 2012-02-02 US claimed
US-8012277-B2 Mixture with activator; desentization melt ALLIANT TECHSYSTEMS INC. (US) 2011-09-06 US claimed
US-20080251169-A1 IONIC LIQUID, A METHOD OF SYNTHESIZING AN IONIC LIQUID, A PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID, AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION ALLIANT TECHSYSTEMS INC. (US) 2008-10-16 US claimed
US-8425702-B2 Precursor of an explosive composition including at least one ionic liquid and a method of desensitizing an explosive composition ALLIANT TECHSYSTEMS INC. (US) 2013-04-23 US disclosed
US-20120024437-A1 PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION ALLIANT TECHSYSTEMS INC. (US) 2012-02-02 US disclosed
US-8012277-B2 Mixture with activator; desentization melt ALLIANT TECHSYSTEMS INC. (US) 2011-09-06 US disclosed
US-20080251169-A1 IONIC LIQUID, A METHOD OF SYNTHESIZING AN IONIC LIQUID, A PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID, AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION ALLIANT TECHSYSTEMS INC. (US) 2008-10-16 US disclosed