SCHEMBL28435355

SCHEMBL28435355

Cc1cc(Cl)c(-n2nc(C(N)=S)c(N[SH](=O)=O)c2N)c(Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
GABRP O00591 6/20 0.34
GABRD O14764 6/20 0.34
GABRA1 P14867 6/20 0.34
GABRB1 P18505 6/20 0.34
GABRG2 P18507 6/20 0.34
GABRB3 P28472 6/20 0.34
GABRA5 P31644 6/20 0.34
GABRA3 P34903 6/20 0.34
GABRA2 P47869 6/20 0.34
GABRB2 P47870 6/20 0.34
GABRA4 P48169 6/20 0.34
GABRE P78334 6/20 0.34
GABRA6 Q16445 6/20 0.34
GABRG1 Q8N1C3 6/20 0.34
GABRG3 Q99928 6/20 0.34
GABRQ Q9UN88 6/20 0.34
SRC P12931 2/20 0.33
KDR P35968 2/20 0.33
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29017034 0.76 L3MBTL1 (0.37) L3MBTL1GABRPGABRDGABRA1GABRB1
SCHEMBL21815688 0.75 L3MBTL1 (0.36) L3MBTL1GABRPGABRDGABRA1GABRB1
SCHEMBL41425 0.72 L3MBTL1 (0.34) L3MBTL1GABRPGABRDGABRA1GABRB1
SCHEMBL677097 0.69 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7963111 0.64 KDR (0.48) L3MBTL1GABRPGABRDGABRA1GABRB1
SCHEMBL7667230 0.62 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7667394 0.62 GABRP (0.62) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1572492 0.60 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL6709955 0.60 GABRP (0.47) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL13515127 0.60 GABRP (0.38) L3MBTL1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113286513-A Synergistic pesticide compositions and methods for delivering insecticidal active ingredients 0903608BC有限公司 2021-08-20 CN disclosed
CN-113163763-A Synergistic pesticidal compositions and methods for delivering active ingredients 0903608BC有限公司 2021-07-23 CN disclosed
CN-111565571-A Synergistic pesticidal compositions and methods for delivery of active ingredients 0903608 B.C.有限公司 2020-08-21 CN disclosed
CN-111565572-A Synergistic pesticidal compositions and methods for delivering active ingredients 0903608 B.C.有限公司 2020-08-21 CN disclosed