Terephthalic Acid

Terephthalic Acid

SCHEMBL2843556

CCOC(N)=O.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.62
ALDH1A1 P00352 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CYP1A2 P05177 2/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAOA P21397 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
PLA2G4B P0C869 1/20 0.49
MAPT P10636 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
PARP10 Q53GL7 2/20 0.47
PARP15 Q460N3 1/20 0.47
CA12 O43570 1/20 0.47
ESR1 P03372 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
ESR2 Q92731 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL28885479 0.94 ALOX15 (0.56) ALOX15ALDH1A1SMN1; SMN2CYP1A2LMNA
Aminobenzoic Acid SCHEMBL28207996 0.93 LMNA (0.62) ALOX15ALDH1A1SMN1; SMN2CYP1A2LMNA
Benzoic Acid SCHEMBL27915617 0.92 ALOX15 (0.58) ALOX15ALDH1A1SMN1; SMN2CYP1A2LMNA
Urethane SCHEMBL9789799 0.87 KDM4E (0.54) ALOX15CYP1A2LMNACYP3A4MAOA
4-Nitrobenzoic Acid SCHEMBL28690722 0.85 TDP1 (0.64) ALDH1A1SMN1; SMN2LMNATSHRPLA2G4B
Terephthalamide SCHEMBL5705650 0.85 ALOX15 (0.65) ALOX15ALDH1A1SMN1; SMN2CYP1A2LMNA
Urethane SCHEMBL2404606 0.82 ALOX15 (0.83) ALOX15ALDH1A1SMN1; SMN2CYP1A2LMNA
Urethane SCHEMBL27766653 0.82
SCHEMBL27063 0.81 CA1 (0.70) ALDH1A1SMN1; SMN2CYP1A2LMNACYP3A4
Terephthalic Acid SCHEMBL28214245 0.81 CA1 (0.70) ALDH1A1SMN1; SMN2CYP1A2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11964810-B2 Fracturable container SANDS INNOVATIONS LTD (AU) 2024-04-23 US claimed
US-20230375726-A1 SCINTILLATOR ARRAY, METHOD FOR MANUFACTURING SCINTILLATOR ARRAY, RADIATION DETECTOR, AND RADIATION INSPECTION DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2023-11-23 US claimed
CN-110730750-B Breakable container 桑德斯创新有限公司 2022-11-08 CN claimed
CN-114787048-A Container 桑德斯创新有限公司 2022-07-22 CN claimed
WO-2021068026-A1 A CONTAINER SANDS INNOVATIONS LTD (AU) 2021-04-15 WO claimed
US-20200156842-A1 FRACTURABLE CONTAINER SANDS INNOVATIONS LTD (AU) 2020-05-21 US claimed
EP-3609802-A1 FRACTURABLE CONTAINER Sands Innovations Ltd (AU) 2020-02-19 EP claimed
CN-110730750-A Breakable container 桑德斯创新有限公司 2020-01-24 CN claimed
US-20030148866-A1 Forming roll covers VOITH FABRICS HEIDENHEIM GMBH (DE) 2003-08-07 US claimed
US-6325747-B1 Martial arts training device CENTER RING MARTIAL ARTS, INC. 2001-12-04 US claimed
EP-0574284-B1 Case provided with closure having no moving parts OREAL (FR) 1997-01-02 EP claimed
EP-0421466-A2 Coating apparatus FUJI PHOTO FILM CO., LTD. (JP) 1991-04-10 EP claimed
US-4978999-A Fiber reinforced cleaning blade XEROX CORPORATION (US) 1990-12-18 US claimed
US-4950532-A SURFACE SMOOTHNESS BY PREHEATING THE COMPOSITE AND MOLDING UNDER CONTROLLED RHEOLOGICAL CONDITIONS AZDEL, INC. (US) 1990-08-21 US claimed
US-4853419-A POLYISOCYANURATE/URETHANE COPOLYMERS USING A WASTE POLYETHYLENE TEREPHTHALATE DIGESTED BY A POLYACID-CONTAINING POLYLOL; PREMIX STORAGE STABILITY SLOSS INDUSTRIES CORPORATION (US) 1989-08-01 US claimed
JP-3250043-A None JP disclosed
JP-5200872-A None JP disclosed
US-4469718-A CROSSLINKING BY MELTING IN PRESENCE OF OXYGEN THE FURUKAWA ELECTRIC CO., LTD. (JP) 1984-09-04 US disclosed
US-4338243-A Polyethylene terephthalate blends E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-07-06 US disclosed
US-4248652-A Method of making leatherlike materials (A) INMONT CORPORATION (US) 1981-02-03 US disclosed