Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urethane SCHEMBL27620953 | 0.87 | ALOX5 (0.60) | TDP1SRD5A2TSHRKMT2AMEN1 | |
| 4-Nitrobenzoic Acid SCHEMBL21644729 | 0.86 | TDP1 (0.66) | TDP1SRD5A2KMT2AMEN1SMN1; SMN2 | |
| Nitrobenzene SCHEMBL27659551 | 0.86 | ALDH1A1 (0.53) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| Terephthalic Acid SCHEMBL2843556 | 0.85 | ALOX15 (0.62) | SRD5A2TSHRKMT2AMEN1SMN1; SMN2 | |
| 4-Nitrobenzoic Acid SCHEMBL21246859 | 0.84 | TDP1 (0.78) | TDP1SRD5A2TSHRKMT2AMEN1 | |
| 4-Nitrobenzoic Acid SCHEMBL27935693 | 0.82 | TDP1 (0.81) | TDP1SRD5A2TSHRKMT2AMEN1 | |
| 4-Nitrobenzoic Acid SCHEMBL27900174 | 0.82 | TDP1 (0.88) | TDP1SRD5A2TSHRKMT2AMEN1 | |
| Terephthalic Acid SCHEMBL28885479 | 0.80 | ALOX15 (0.56) | SRD5A2TSHRKMT2AMEN1SMN1; SMN2 | |
| 4-Nitrobenzoic Acid SCHEMBL8766543 | 0.80 | TDP1 (0.91) | TDP1SRD5A2TSHRKMT2AMEN1 | |
| 4-Nitrobenzoic Acid SCHEMBL43476 | 0.80 | TDP1 (1.00) | TDP1SRD5A2TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |