SCHEMBL28436618

SCHEMBL28436618

C=Cc1ccccc1C=O.c1ccc2c(c1)O2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.54
LMNA P02545 2/20 0.54
MEN1 O00255 2/20 0.54
THRB P10828 1/20 0.54
BLM P54132 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 4/20 0.40
NTSR1 P30989 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
TSHR P16473 1/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
CYP2A6 P11509 2/20 0.38
IMPDH2 P12268 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
PTPN1 P18031 4/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23559 0.87 LMNA (0.72) KMT2ALMNAMEN1THRBBLM
Sulfuric Acid SCHEMBL379146 0.77 TDP1 (0.56) KMT2ALMNAMEN1THRBBLM
Styrene SCHEMBL8168630 0.77 ALDH1A1 (0.61) KMT2ALMNAMEN1THRBBLM
Ethylene Glycol SCHEMBL28223913 0.77 LMNA (0.56) KMT2ALMNAMEN1THRBBLM
Adamantane SCHEMBL29163783 0.75 LMNA (0.54) KMT2ALMNAMEN1THRBBLM
Aniline SCHEMBL27370260 0.75 LMNA (0.54) KMT2ALMNAMEN1THRBBLM
SCHEMBL15151084 0.75 AHR (0.50) KMT2ALMNAMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL28856421 0.74 LMNA (0.87) KMT2ALMNAMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL4953869 0.74 LMNA (1.00) KMT2ALMNAMEN1THRBBLM
Ortho-Phthalaldehyde SCHEMBL33393 0.74 LMNA (1.00) KMT2ALMNAMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111278927-B Curable polyorganosiloxane composition, cured body obtained by curing the composition, and electronic device comprising the same 美国陶氏有机硅公司 2022-06-03 CN disclosed
CN-111278927-A Curable polyorganosiloxane composition, cured body obtained by curing the composition, and electronic device comprising the same 美国陶氏有机硅公司 2020-06-12 CN disclosed