Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL968452 | 0.91 | ALDH1A1 (0.48) | TDP1LMNAKMT2AMEN1THRB | |
| SCHEMBL23559 | 0.89 | LMNA (0.72) | TDP1LMNAKMT2AMEN1THRB | |
| Ethylene Glycol SCHEMBL28223913 | 0.83 | LMNA (0.56) | TDP1LMNAKMT2AMEN1THRB | |
| Vinylsulfonic Acid SCHEMBL28173703 | 0.82 | TDP1 (0.45) | TDP1LMNAKMT2AMEN1THRB | |
| Styrene SCHEMBL8087550 | 0.81 | ALDH1A1 (0.58) | TDP1LMNAKMT2AMEN1ALDH1A1 | |
| Vinylsulfonic Acid SCHEMBL28148853 | 0.80 | TDP1 (0.43) | TDP1LMNAKMT2AMEN1THRB | |
| Formic Acid SCHEMBL28194049 | 0.79 | ALDH1A1 (0.50) | TDP1LMNAKMT2AMEN1THRB | |
| Styrene SCHEMBL8168630 | 0.78 | ALDH1A1 (0.61) | TDP1LMNAKMT2AMEN1THRB | |
| Sulfuric Acid SCHEMBL8445673 | 0.78 | TRIM24 (0.52) | LMNAKMT2AMEN1TRIM24TRIM33 | |
| Sulfuric Acid SCHEMBL3091932 | 0.78 | ACHE (0.49) | LMNAKMT2AMEN1ALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232092-B | Antimicrobial compositions containing cationic active ingredients | 艺康美国股份有限公司 | 2020-07-14 | — | — | CN | claimed |
| US-10159246-B2 | Copolymers of N-vinylcarboxamide and diallyldialkylammonium salt as dispersant for agrochemical formulations | BASF SE (DE) | 2018-12-25 | — | — | US | claimed |
| EP-2109441-B1 | POLYSILOXANE BLOCK COPOLYMERS | BASF SE (DE) | 2016-01-27 | — | — | EP | claimed |
| EP-2713720-B1 | COPOLYMERS OF N-VINYLCARBOXAMIDE AND DIALLYLDIALKYLAMMONIUM SALT AS DISPERSANT FOR AGROCHEMICAL FORMULATIONS | BASF SE (DE) | 2016-01-06 | — | — | EP | claimed |
| US-20140080702-A1 | Copolymers of N-vinylcarboxamide and diallyldialkylammonium salt as dispersant for agrochemical formulations | BASF SE (DE) | 2014-03-20 | — | — | US | claimed |
| EP-2163553-B1 | ARENE CONNECTED POLYAMINE MACRORING DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO LTD (CN) | 2013-12-25 | — | — | EP | claimed |
| US-8450353-B2 | Topical compositions containing desthiobiotin and its derivatives and a method of treating skin | AVON PRODUCTS, INC. (US) | 2013-05-28 | — | — | US | claimed |
| US-8420626-B2 | Arene connected polyamine macrocyclic derivatives, preparation methods and pharmaceutical uses thereof | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2013-04-16 | — | — | US | claimed |
| US-20130012430-A1 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-01-10 | — | — | US | claimed |
| US-20130005739-A1 | PHARMACEUTICAL PREPARATIONS COMPRISING A COS RELEASING COMPOUND | LUDWIG BOLTZMANN CLUSTER FUER KARDIOVASKULAERE FORSCHUNG (AT) | 2013-01-03 | — | — | US | claimed |
| US-20050261419-A1 | High molecular weight cationic polymers obtained by post-polymerization crosslinking reaction | SONG ZHIQIANG | 2005-11-24 | — | — | US | claimed |
| EP-1539827-A1 | HIGH MOLECULAR WEIGHT CATIONIC POLYMERS OBTAINED BY POST-POLYMERISATION CROSSLINKING REACTION | Ciba Specialty Chemicals Water Treatments Limited (GB) | 2005-06-15 | — | — | EP | claimed |
| WO-2004101882-A1 | USE OF WATER-SOLUBLE CROSSLINKED CATIONIC POLYMERS FOR CONTROLLING DEPOSITION OF PITCH AND STICKIES IN PAPERMAKING | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-11-25 | — | — | WO | claimed |
| US-20040226676-A1 | Use of water-soluble crosslinked cationic polymers for controlling deposition of pitch and stickies in papermaking | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-11-18 | — | — | US | claimed |
| WO-2004050701-A1 | BONE GROWTH FACTOR | OSTEOPHARM INC. (CA) | 2004-06-17 | — | — | WO | claimed |
| WO-2004018524-A1 | HIGH MOLECULAR WEIGHT CATIONIC POLYMERS OBTAINED BY POST-POLYMERISATION CROSSLINKING REACTION | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-03-04 | — | — | WO | claimed |
| US-20040034156-A1 | High molecular weight cationic polymers obtained by post-polymerization crosslinking reaction | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2004-02-19 | — | — | US | claimed |
| US-20030232800-A1 | Non-symmetric tripyrranes in the synthesis of novel macrocycles | UNIVERSITY OF TEXAS | 2003-12-18 | — | — | US | claimed |
| WO-2002017925-A1 | NON-SYMMETRIC TRIPYRRANNES IN THE SYNTHESIS OF NOVEL MACROCYCLES | PHARMACYCLICS, INC. (US) | 2002-03-07 | — | — | WO | claimed |
| US-4395402-A | ENKEPHALIN IN HIBITOR, SYNERGISTIC COMPOUND WITH MORPHINE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KANKYU KAI (JP) | 1983-07-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080702-A1 | Copolymers of N-vinylcarboxamide and diallyldialkylammonium salt as dispersant for agrochemical formulations | DDT, CDIPT, ACMSD | TDP1 2709/4885LMNA 4232/4885KMT2A 416/4885 |
| US-10159246-B2 | Copolymers of N-vinylcarboxamide and diallyldialkylammonium salt as dispersant for agrochemical formulations | DDT, CDIPT, ACMSD | TDP1 2709/4885LMNA 4232/4885KMT2A 416/4885 |
| US-20130012430-A1 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE | HPN, PRSS1, PRSS3 | TDP1 2733/4885LMNA 2150/4885KMT2A 3959/4885 |
| US-20130005739-A1 | PHARMACEUTICAL PREPARATIONS COMPRISING A COS RELEASING COMPOUND | VIP, CRH, ADCYAP1R1 | TDP1 2484/4885LMNA 1473/4885KMT2A 4871/4885 |
| US-20030232800-A1 | Non-symmetric tripyrranes in the synthesis of novel macrocycles | NUP188, TRIP13, NUP160 | TDP1 1284/4885LMNA 2222/4885KMT2A 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.