SCHEMBL28436718

SCHEMBL28436718

CC(C)(CCOCC(=O)O)CCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34465027 0.86 DUT (0.41) DUT
SCHEMBL4598387 0.84 DUT (0.40) DUT
SCHEMBL15061387 0.83 DUT (0.36) DUT
SCHEMBL21068488 0.81 GAA (0.32)
SCHEMBL21068886 0.79 EPHX2 (0.38) DUT
SCHEMBL21068889 0.79 EPHX2 (0.38) DUT
SCHEMBL2163046 0.76 TSHR (0.40)
SCHEMBL25337442 0.75
SCHEMBL25339258 0.75 BACE1 (0.32)
SCHEMBL29132502 0.75 LMNA (0.37) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111491623-A Compounds and their use in the treatment of cancer 阿斯利康(瑞典)有限公司 2020-08-04 CN disclosed