Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23461816 | 0.85 | LMNA (0.41) | LMNAHSD17B10CHRM2CHRM4CHRM5 | |
| SCHEMBL23067127 | 0.82 | LMNA (0.38) | LMNAHSD17B10CHRM2CHRM4CHRM5 | |
| SCHEMBL28704916 | 0.81 | TSHR (0.37) | LMNAHSD17B10CHRM2CHRM4CHRM5 | |
| SCHEMBL16197570 | 0.81 | DUT (0.39) | LMNAHSD17B10CHRM2CHRM4CHRM5 | |
| SCHEMBL368374 | 0.76 | DUT (0.30) | DUT | |
| SCHEMBL28436718 | 0.75 | DUT (0.32) | DUT | |
| SCHEMBL2883658 | 0.74 | DUT (0.31) | DUT | |
| SCHEMBL30559860 | 0.74 | LMNA (0.48) | LMNAHSD17B10CHRM2CHRM4CHRM5 | |
| SCHEMBL25339258 | 0.73 | BACE1 (0.32) | — | |
| SCHEMBL25337442 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829555-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-09-29 | — | — | CN | disclosed |