Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484192 | 0.86 | MYC (0.46) | L3MBTL1POLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL152899 | 0.85 | HSP90AA1 (0.50) | L3MBTL1POLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL8610906 | 0.85 | NPC1 (0.46) | L3MBTL1TDP1ALDH1A1HSP90AA1TRAP1 | |
| SCHEMBL30637639 | 0.85 | NPC1 (0.46) | L3MBTL1TDP1ALDH1A1HSP90AA1TRAP1 | |
| SCHEMBL30928942 | 0.85 | NPC1 (0.46) | L3MBTL1TDP1ALDH1A1HSP90AA1TRAP1 | |
| SCHEMBL154462 | 0.85 | NOTUM (0.50) | L3MBTL1POLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL2581642 | 0.82 | ALDH1A1 (0.40) | L3MBTL1POLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL1271471 | 0.82 | TDP1 (0.48) | L3MBTL1POLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL9429195 | 0.82 | FABP4 (0.57) | L3MBTL1POLBAPEX1TDP1ALDH1A1 | |
| SCHEMBL16719951 | 0.82 | POLB (0.48) | L3MBTL1POLBAPEX1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491623-A | Compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2020-08-04 | — | — | CN | disclosed |