Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005218 | 0.83 | HTT (0.53) | HTTTERTCA1CA2LMNA | |
| SCHEMBL1533960 | 0.79 | HTT (0.45) | HTTTERTCA1CA2LMNA | |
| SCHEMBL28808933 | 0.79 | HTT (0.47) | HTTTERTCA1CA2LMNA | |
| SCHEMBL18984654 | 0.75 | GAA (0.62) | CA1CA2LMNASMN1; SMN2GAA | |
| SCHEMBL1908393 | 0.75 | HTT (0.44) | HTTTERTCA1CA2LMNA | |
| SCHEMBL1001154 | 0.72 | TERT (0.55) | HTTTERTCA1CA2LMNA | |
| Methyl Alcohol SCHEMBL21523587 | 0.71 | GAA (0.56) | HTTCA1CA2LMNASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL28016005 | 0.71 | GAA (0.56) | HTTCA1CA2LMNASMN1; SMN2 | |
| Methyl Alcohol SCHEMBL3617702 | 0.71 | GAA (0.56) | HTTCA1CA2LMNASMN1; SMN2 | |
| SCHEMBL2138368 | 0.71 | GAA (0.62) | CA1CA2LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111435705-A | Repairing agent and repairing method thereof and method for preparing photoelectric film | 杭州纤纳光电科技有限公司 | 2020-07-21 | — | — | CN | disclosed |