Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28439182 | 0.85 | HSP90AA1 (0.50) | POLBHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28446740 | 0.80 | HSP90AA1 (0.46) | POLBHTTKMT2AALDH1A1MAPT | |
| SCHEMBL5186846 | 0.79 | NCF1 (0.56) | POLBMEN1KMT2ANCF1ALDH1A1 | |
| SCHEMBL28442986 | 0.79 | POLB (0.54) | PKMPOLBHTTALDH1A1CYP3A4 | |
| SCHEMBL28270265 | 0.78 | PKM (0.68) | PKMPOLBHTTMEN1KMT2A | |
| SCHEMBL14498086 | 0.78 | HTT (0.65) | PKMHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL9914248 | 0.78 | HTT (0.65) | PKMHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28007445 | 0.77 | KDM4E (0.64) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28440582 | 0.76 | KDM4E (0.57) | PKMPOLBHTTKMT2AALDH1A1 | |
| SCHEMBL10034462 | 0.75 | HTT (0.61) | PKMHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096186-B | Synthesis method of 2-arylsulfonyl quinoline derivative | 中南大学 | 2020-08-04 | — | — | CN | disclosed |