Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28440582 | 0.83 | KDM4E (0.57) | PKMHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5670238 | 0.82 | HDAC1 (0.53) | PKMHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL30483849 | 0.82 | HDAC1 (0.53) | PKMHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28271752 | 0.80 | HTT (0.65) | PKMHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL31315377 | 0.80 | AKR1B1 (0.47) | PKMHTTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL8559792 | 0.80 | HTR6 (0.49) | PKMHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28437060 | 0.78 | PKM (0.49) | PKMHTTPOLBALDH1A1KDM4E | |
| SCHEMBL14488046 | 0.78 | PKM (0.66) | PKMHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8566588 | 0.76 | HDAC1 (0.46) | PKMHTTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8236987 | 0.76 | PKM (0.63) | PKMHTTPOLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285543-B | Sulfonylation method of halogenated quinoline and aryl sulfonyl hydrazine | 南京工业大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-119285543-A | Sulfonylation method of halogenated quinoline and aryl sulfonyl hydrazine | 南京工业大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-109096186-B | Synthesis method of 2-arylsulfonyl quinoline derivative | 中南大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-109096186-A | A kind of synthetic method of 2- arylsulfonyl quinoline | 中南大学 | 2018-12-28 | — | — | CN | disclosed |