Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437842 | 1.00 | RAB9A (0.37) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL28436360 | 0.93 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL28431814 | 0.93 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL28436362 | 0.93 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL28431815 | 0.93 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL28444438 | 0.90 | SMN1; SMN2 (0.39) | RAB9AMEN1ALDH1A1KMT2ADPP4 | |
| SCHEMBL28443110 | 0.89 | DPP4 (0.36) | RAB9AALDH1A1KMT2AHSD17B10DPP4 | |
| SCHEMBL28443109 | 0.89 | DPP4 (0.36) | RAB9AALDH1A1KMT2AHSD17B10DPP4 | |
| SCHEMBL28441130 | 0.89 | CYP3A4 (0.37) | RAB9AMEN1ALDH1A1KMT2ADPP4 | |
| SCHEMBL28437363 | 0.88 | DPP4 (0.37) | DPP4DPP7CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-A | Coumarin derivatives, preparation method thereof and application thereof in cancer treatment | 利德发现中心有限责任公司 | 2020-07-07 | — | — | CN | claimed |
| CN-111386261-A | Coumarin derivatives, preparation method thereof and application thereof in cancer treatment | 利德发现中心有限责任公司 | 2020-07-07 | — | — | CN | disclosed |