SCHEMBL2843845

SCHEMBL2843845

C=C(CCC(N)OCC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
GRM1 Q13255 1/20 0.38
GRM2 Q14416 1/20 0.38
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36
GABRA4 P48169 2/20 0.36
GABRE P78334 2/20 0.36
GABRA6 Q16445 2/20 0.36
GABRG1 Q8N1C3 2/20 0.36
GABRG3 Q99928 2/20 0.36
GABRQ Q9UN88 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486621 0.81 TET2 (0.33) GRIK1GRIK2GRM1GRM2GABRP
SCHEMBL3748664 0.81 TET2 (0.38) GRIK1GRIK2GRM1GRM2GABRP
SCHEMBL828545 0.79 GABRP (0.33) GRIK1GRIK2GRM1GRM2GABRP
Hydrochloric Acid SCHEMBL27326101 0.79 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2TET2
SCHEMBL50117 0.78 GABRP (0.60) GRIK1GRIK2GRM1GRM2GABRP
SCHEMBL14151468 0.78 TET2 (0.31) GRIK1GRIK2GRM1GRM2TET2
SCHEMBL475008 0.76 TET2 (0.31) TET2TET3TET1
SCHEMBL9632367 0.76 CHRM1 (0.33) TET2TET3TET1
SCHEMBL7171781 0.74 EPHX1 (0.33) GRIK1GRIK2GRM1GRM2TET2
Formic Acid SCHEMBL28776528 0.74 GABRP (0.50) GRIK1GRIK2GRM1GRM2GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632954-B2 Method for making a lithographic printer plate precursor AGFA GRAPHICS NV (BE) 2014-01-21 US disclosed
US-8415087-B2 Method of making a lithographic printing plate AGFA GRAPHICS NV (BE) 2013-04-09 US disclosed
US-20100209851-A1 METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE AGFA GRAPHICS NV (BE) 2010-08-19 US disclosed
US-20100129756-A1 GUM SOLUTION FOR DEVELOPING AND GUMMING A PHOTOPOLYMER PRINTING PLATE AGFA GRAPHICS N.V. (BE) 2010-05-27 US disclosed
US-20100129755-A1 METHOD FOR MAKING A LITHOGRAPHIC PRINTER PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-05-27 US disclosed