Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562771 | 0.90 | ALDH1A1 (0.44) | KDM4EPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28438516 | 0.85 | MEN1 (0.43) | CYP1A2KDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28444191 | 0.84 | MEN1 (0.42) | HSD17B2CYP1A2KDM4EPOLBALDH1A1 | |
| SCHEMBL28440077 | 0.83 | ALDH1A1 (0.41) | CYP1A2HSP90AA1HSP90AB1KDM4EPOLB | |
| SCHEMBL28443344 | 0.83 | ALDH1A1 (0.41) | CYP1A2KDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28640296 | 0.82 | KMT2A (0.50) | KDM4EPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28436017 | 0.80 | ALDH1A1 (0.42) | KDM4EPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28438519 | 0.80 | ALDH1A1 (0.39) | CYP1A2KDM4EPOLBALDH1A1GAA | |
| SCHEMBL28421212 | 0.79 | KMT2A (0.50) | KDM4EPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10734200 | 0.78 | RAB9A (0.52) | CYP1A2POLBALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499545-B | Preparation method of p-amino substituted phenol compound | 武汉英纳氏药业有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-111499545-A | Preparation method of p-amino substituted phenol compound | 湖北工业大学 | 2020-08-07 | — | — | CN | disclosed |