Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734200 | 0.86 | RAB9A (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28421212 | 0.85 | KMT2A (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10562771 | 0.85 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28631794 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10881230 | 0.83 | ALDH1A1 (0.66) | KMT2AGLAMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28438529 | 0.82 | HSD17B2 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10734051 | 0.82 | RAB9A (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28640254 | 0.81 | MEN1 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28651914 | 0.81 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27619730 | 0.79 | ALDH1A1 (0.58) | KMT2AGLAMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248410-B | Preparation method of silver-mediated N-aroyl hydrazine compound | 湖北工业大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-113248410-A | Preparation method of silver-mediated N-arylhydrazide compound | 湖北工业大学 | 2021-08-13 | — | — | CN | disclosed |