Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.65 |
| ▸ | RAD52 | P43351 | 2/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | PRKCG | P05129 | 1/20 | 0.55 |
| ▸ | PRKCB | P05771 | 1/20 | 0.55 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | PRKCH | P24723 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10884283 | 1.00 | DNM1 (0.65) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| Hydrochloric Acid SCHEMBL118329 | 1.00 | DNM1 (0.65) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| Hydrochloric Acid SCHEMBL115731 | 1.00 | DNM1 (0.65) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| Hydrochloric Acid SCHEMBL10396250 | 1.00 | DNM1 (0.65) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| Hydrochloric Acid SCHEMBL116528 | 1.00 | DNM1 (0.65) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| SCHEMBL8855785 | 0.98 | DNM1 (0.64) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| SCHEMBL8855808 | 0.98 | DNM1 (0.64) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| Hydrochloric Acid SCHEMBL18191791 | 0.98 | DNM1 (0.61) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| SCHEMBL8855809 | 0.98 | DNM1 (0.64) | DNM1RAD52APAF1HSP90AA1PRKD3 | |
| SCHEMBL8855776 | 0.98 | DNM1 (0.64) | DNM1RAD52APAF1HSP90AA1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419737-A | Solid hair care agent and preparation method thereof | 大连交通大学 | 2020-07-17 | — | — | CN | claimed |
| CN-114259414-A | Hair cosmetic | 株式会社资生堂 | 2022-04-01 | — | — | CN | disclosed |
| CN-111419737-A | Solid hair care agent and preparation method thereof | 大连交通大学 | 2020-07-17 | — | — | CN | disclosed |