Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325948 | 0.80 | MAPT (0.47) | HTR1BMAPTMEN1KMT2ALMNA | |
| SCHEMBL7076726 | 0.78 | GABRA1 (0.40) | GABRA1GABRB2ELANE | |
| Hydrochloric Acid SCHEMBL11421175 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2KMT2AELANE | |
| SCHEMBL10345092 | 0.76 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL7532649 | 0.75 | GABRA1 (0.38) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL8053687 | 0.74 | GABRA1 (0.37) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL10494208 | 0.74 | GABRA1 (0.34) | GABRA1GABRB2KMT2A | |
| SCHEMBL11677650 | 0.73 | GABRA1 (0.56) | GABRA1GABRB2MAPTMAPK1HSD17B10 | |
| SCHEMBL5685706 | 0.73 | GABRA1 (0.52) | GABRA1GABRB2HTTELANEL3MBTL1 | |
| SCHEMBL1842279 | 0.71 | TRPA1 (0.40) | GABRA1GABRB2HTR1BMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111529684-A | Use of oral sustained release compositions containing cyclosporin | 卓越治疗有限公司 | 2020-08-14 | — | — | CN | disclosed |