Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648313 | 0.88 | MAPT (0.42) | MAPTHTR1BKEAP1POLBTRPA1 | |
| SCHEMBL3720870 | 0.86 | MAPT (0.47) | MAPTHTR1BKEAP1POLBTRPA1 | |
| SCHEMBL14271680 | 0.83 | MAPT (0.44) | MAPTHTR1BKEAP1POLBTRPA1 | |
| SCHEMBL516150 | 0.83 | MAPT (0.44) | MAPTHTR1BKEAP1POLBTRPA1 | |
| SCHEMBL1592873 | 0.81 | NISCH (0.47) | SLC6A2SLC6A4SLC6A3KDM4EMEN1 | |
| Bromide SCHEMBL25206394 | 0.81 | MAPT (0.43) | MAPTHTR1BKEAP1POLBTRPA1 | |
| SCHEMBL28439986 | 0.80 | GABRA1 (0.39) | MAPTHTR1BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16955002 | 0.80 | MAPT (0.46) | MAPTHTR1BKEAP1POLBTRPA1 | |
| SCHEMBL16234636 | 0.77 | TSHR (0.46) | MAPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL4778014 | 0.77 | MAPT (0.40) | MAPTHTR1BKEAP1POLBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138653-A9 | THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME | NASHUA CORP (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2006138653-A1 | THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME | NASHUA CORPORATION (US) | 2006-12-28 | — | — | WO | disclosed |