SCHEMBL28440132

SCHEMBL28440132

CN1CCN(C(C)(C)C)C(C=O)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1915246 0.74 HTT (0.50) HTT
SCHEMBL799862 0.74 NCF1 (0.30)
SCHEMBL13448442 0.71 HTT (0.38) HTT
SCHEMBL12435686 0.71 HTT (0.38) HTT
SCHEMBL24348673 0.70 LMNA (0.31) HTT
SCHEMBL12312746 0.70 LMNA (0.31) HTT
SCHEMBL24625325 0.70 LMNA (0.31) HTT
SCHEMBL12312768 0.69 HTT (0.41) HTT
SCHEMBL5711046 0.69 HTT (0.36) HTT
SCHEMBL22304339 0.68 HTT (0.30) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272301-B Heterocyclic compound, intermediate, preparation method and application thereof 武汉朗来科技发展有限公司 2024-04-26 CN disclosed
CN-111377917-B Heterocyclic compound, intermediate, preparation method and application thereof 武汉朗来科技发展有限公司 2022-12-06 CN disclosed
CN-113272301-A Heterocyclic compound, intermediate, preparation method and application thereof 武汉朗来科技发展有限公司 2021-08-17 CN disclosed
CN-111377917-A Heterocyclic compound, intermediate, preparation method and application thereof 武汉朗来科技发展有限公司 2020-07-07 CN disclosed