Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22506783 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22506776 | 0.92 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL24137202 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22795687 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22497583 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL24137175 | 0.90 | ADRB2 (0.45) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL24137165 | 0.89 | ADRB2 (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22506773 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22497602 | 0.89 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL24137179 | 0.88 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320581-A | Synthesis method of quinoline carboxylic ester | 山东省联合农药工业有限公司 | 2020-06-23 | — | — | CN | disclosed |