Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137194 | 0.91 | ADRB2 (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL24137179 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL28440261 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL24137167 | 0.88 | KDM4E (0.42) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL22506776 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL22506783 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL24137202 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL24137175 | 0.84 | ADRB2 (0.45) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL22497602 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL24137165 | 0.83 | ADRB2 (0.47) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| EP-3929180-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shandong United Pesticide Industry Co., Ltd. (CN) | 2021-12-29 | — | — | EP | disclosed |
| WO-2020199981-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | 山东省联合农药工业有限公司 | 2020-10-08 | — | — | WO | disclosed |
| WO-2020199981-A1 | QUINOLINE CARBOXYLIC ACID ESTER COMPOUND AND PREPARATION METHOD AND USE THEREOF | 山东省联合农药工业有限公司 | 2020-10-08 | — | — | WO | disclosed |
| CN-110066245-B | Quinoline carboxylic ester compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-09-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SDHA, GLUL, PGLS | KDM4E 1227/4885ALDH1A1 632/4885LMNA 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.