SCHEMBL28440703

SCHEMBL28440703

c1ccc2cc3cc(SC4CCCCC4)ccc3cc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.51
MAOB P27338 4/20 0.51
AR P10275 1/20 0.39
PTGIR P43119 1/20 0.37
CYP1A2 P05177 1/20 0.36
GRM5 P41594 1/20 0.36
ALDH1A1 P00352 3/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HIF1A Q16665 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HBB P68871 1/20 0.36
FAAH O00519 1/20 0.36
EPHX1 P07099 1/20 0.36
MAPK1 P28482 2/20 0.35
MAPT P10636 4/20 0.35
HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22288286 0.94 MAOA (0.53) MAOAMAOBARPTGIRCYP1A2
SCHEMBL23323158 0.92 MAOA (0.51) MAOAMAOBARCYP1A2GRM5
SCHEMBL22288156 0.84 MAOA (0.47) MAOAMAOBCYP1A2ALDH1A1HSD17B10
SCHEMBL8956123 0.80 MAOA (0.77) MAOAMAOBARPTGIRCASP1
SCHEMBL19890876 0.78 MAOA (0.55) MAOAMAOBARPTGIRCYP1A2
SCHEMBL8955927 0.77 MAOA (0.76) MAOAMAOBARPTGIRCYP1A2
SCHEMBL8955041 0.77 MAOA (0.52) MAOAMAOBARPTGIR
SCHEMBL10446206 0.76 TXN (0.45) MAOAMAOBTDP1FAAHEPHX1
SCHEMBL6181094 0.76 SLC6A4 (0.47) MAOAMAOBCYP1A2SLC6A4SLC6A3
SCHEMBL15270965 0.76 MAOA (0.57) MAOAMAOBPTGIRALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed