Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288286 | 0.98 | MAOA (0.53) | MAOAMAOBCYP1A2GRM5AR | |
| SCHEMBL28440703 | 0.92 | MAOA (0.51) | MAOAMAOBCYP1A2GRM5AR | |
| SCHEMBL22288156 | 0.84 | MAOA (0.47) | MAOAMAOBCYP1A2MAPTCYP1A1 | |
| SCHEMBL6181094 | 0.83 | SLC6A4 (0.47) | MAOAMAOBCYP1A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4768437 | 0.82 | SLC6A4 (0.46) | MAOAMAOBCYP1A2SLC6A4SLC6A3 | |
| SCHEMBL10446206 | 0.79 | TXN (0.45) | MAOAMAOBMAPTEPHX1SLC6A4 | |
| SCHEMBL6931559 | 0.78 | NFKB1 (0.41) | CYP1A2GRM5EPHX1CYP3A4 | |
| SCHEMBL23295277 | 0.78 | MAOA (0.65) | MAOAMAOBARMAPTKDM4E | |
| SCHEMBL19890876 | 0.77 | MAOA (0.55) | MAOAMAOBCYP1A2ARMAPT | |
| SCHEMBL8955927 | 0.77 | MAOA (0.76) | MAOAMAOBCYP1A2ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3592729-B1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-06-30 | — | — | EP | disclosed |
| EP-3592729-B1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-06-30 | — | — | EP | disclosed |
| US-20210130286-A1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130286-A1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | AOX1, TYR, CXXC4 | MAOA 38/4885MAOB 35/4885CYP1A2 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.