Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27667340 | 0.82 | ALDH1A1 (0.39) | ALDH1A1FFAR2TSHRNOS1HSD17B10 | |
| SCHEMBL27600811 | 0.82 | ALDH1A1 (0.39) | ALDH1A1FFAR2TSHRNOS1HSD17B10 | |
| SCHEMBL11318587 | 0.81 | ALDH1A1 (0.52) | ALDH1A1FFAR2TSHRNPC1RAB9A | |
| SCHEMBL28755305 | 0.80 | ALDH1A1 (0.39) | ALDH1A1FFAR2TSHRNPC1RAB9A | |
| SCHEMBL14591145 | 0.78 | FFAR2 (0.49) | ALDH1A1FFAR2TSHRNPC1RAB9A | |
| SCHEMBL7320406 | 0.77 | ALDH1A1 (0.47) | ALDH1A1FFAR2TSHRNOS1HSD17B10 | |
| SCHEMBL27814455 | 0.77 | ALDH1A1 (0.47) | ALDH1A1FFAR2TSHRNPC1RAB9A | |
| SCHEMBL25781210 | 0.77 | ALDH1A1 (0.47) | ALDH1A1FFAR2TSHRNOS1HSD17B10 | |
| SCHEMBL28941701 | 0.76 | PKM (0.47) | ALDH1A1NPC1RAB9AHTTLMNA | |
| SCHEMBL27567713 | 0.76 | METAP1 (0.36) | ALDH1A1FFAR2TSHRNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279852-B | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-111635408-B | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112279852-A | Triazolo-pyrimidine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-111635408-A | Triazolo-pyrimidine compounds and uses thereof | 迪哲（江苏）医药有限公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-111601809-A | Triazolo-pyrimidine compounds and uses thereof | 迪哲（江苏）医药有限公司 | 2020-08-28 | — | — | CN | disclosed |