Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216822 | 0.75 | OPRM1 (0.39) | OPRM1HTR2AHTR2BTACR1 | |
| SCHEMBL8642209 | 0.75 | HTR2A (0.38) | OPRM1HTR2AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL7237713 | 0.69 | KIF11 (0.40) | OPRM1TACR1 | |
| SCHEMBL28536576 | 0.68 | KDM4E (0.40) | OPRM1HTR2ASLC6A2SLC6A4TACR1 | |
| SCHEMBL8642204 | 0.64 | OPRM1 (0.36) | OPRM1HTR2ASLC6A4TACR1 | |
| SCHEMBL30352945 | 0.63 | ARG1 (0.31) | — | |
| SCHEMBL29290911 | 0.62 | OPRM1 (0.43) | OPRM1HTR2ATACR1 | |
| SCHEMBL6847573 | 0.62 | OPRM1 (0.37) | OPRM1HTR2A | |
| SCHEMBL11471276 | 0.62 | OPRM1 (0.40) | OPRM1HTR2ATACR1 | |
| SCHEMBL11451165 | 0.62 | OPRM1 (0.40) | OPRM1HTR2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074816-B | Heterocyclic derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2020-07-17 | — | — | CN | disclosed |