SCHEMBL28440985

SCHEMBL28440985

O=Cc1ccccc1-c1ccc(COCc2ccc(C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.44
MAPT P10636 3/20 0.44
RAB9A P51151 2/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
ATM Q13315 1/20 0.44
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
GAA P10253 2/20 0.42
XDH P47989 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11040033 0.84 RAB9A (0.53) MAPTRAB9AKMT2AMEN1LMNA
SCHEMBL28440984 0.82 RAB9A (0.63) HSP90AB1MAPTRAB9AKMT2AMEN1
SCHEMBL4711414 0.81 ALDH1A1 (0.60) HSP90AB1MAPTRAB9AKMT2AMEN1
SCHEMBL3556722 0.76 ERN1 (0.53) ALDH1A1RXRARXRBRXRGDRD2
SCHEMBL29950910 0.76 ERN1 (0.53) ALDH1A1RXRARXRBRXRGDRD2
SCHEMBL7929310 0.75 XDH (0.40) MAPTRAB9AKMT2AMEN1LMNA
SCHEMBL28618314 0.75 XDH (0.50) MAPTRAB9AKMT2AMEN1LMNA
SCHEMBL12110127 0.74 ALDH1A1 (0.57) HSP90AB1MAPTRAB9AKMT2AMEN1
SCHEMBL2851921 0.73 GAA (0.60) HSP90AB1MAPTRAB9AKMT2AMEN1
SCHEMBL6659668 0.73 ALDH1A1 (0.53) HSP90AB1MAPTRAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108219662-B Water-based ultraviolet curing coating, preparation method and application thereof, and coating product 广州昊毅新材料科技股份有限公司 2020-08-11 CN disclosed