Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325817 | 0.88 | KDM4E (0.76) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL9575455 | 0.77 | KDM4E (0.80) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL31730773 | 0.77 | KDM4E (0.80) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL28026288 | 0.76 | KDM4E (0.66) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL14855680 | 0.75 | KDM4E (0.76) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL14855798 | 0.74 | SMN1; SMN2 (0.75) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL29028434 | 0.74 | KDM4E (0.70) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL22445033 | 0.74 | TSHR (0.74) | LMNAKDM4ETSHRPOLBHSD17B10 | |
| SCHEMBL9183126 | 0.73 | ELANE (0.74) | LMNAKDM4ETSHRPOLBNPSR1 | |
| SCHEMBL11594005 | 0.73 | KDM4E (0.58) | LMNAKDM4ETSHRPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947984-B | Preparation method of pranlukast | 烟台万润药业有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-108947984-B | Preparation method of pranlukast | 烟台万润药业有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-108947984-B | Preparation method of pranlukast | 烟台万润药业有限公司 | 2020-07-07 | — | — | CN | disclosed |