Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11594686 | 0.84 | NPC1 (0.63) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL2356464 | 0.82 | SMN1; SMN2 (0.71) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7832216 | 0.80 | MEN1 (0.68) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL11592326 | 0.80 | F10 (0.66) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL29065716 | 0.79 | LMNA (0.52) | KDM4ELMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL14855964 | 0.79 | SMN1; SMN2 (0.80) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11590186 | 0.78 | SUCNR1 (0.58) | LMNARAB9ANPC1GAAMEN1 | |
| SCHEMBL9575455 | 0.78 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL31730773 | 0.78 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28026288 | 0.77 | KDM4E (0.66) | KDM4ELMNASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088651-A | Acylamino quinophthalone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |