SCHEMBL28442159

SCHEMBL28442159

CCOC(=O)SNCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.47
ALDH1A1 P00352 5/20 0.44
CYP2D6 P10635 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GAA P10253 3/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX15 P16050 1/20 0.34
SOAT1 P35610 1/20 0.34
PPID Q08752 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
TRPA1 O75762 1/20 0.32
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
FFAR3 O14843 1/20 0.31
CDK1 P06493 1/20 0.30
CDK4 P11802 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9129442 0.75 MAPT (0.36) ALDH1A1CYP2D6SMN1; SMN2HSD17B10ALOX15
Ammonia Solution, Strong SCHEMBL10948552 0.68 EGLN1 (0.49) EGLN1ALDH1A1CYP2D6SMN1; SMN2GAA
SCHEMBL27668152 0.68 ALOX15 (0.46) ALDH1A1CYP2D6GAAMGAMSI
SCHEMBL30741390 0.67 GAA (0.74) EGLN1ALDH1A1CYP2D6SMN1; SMN2GAA
SCHEMBL15376 0.67
SCHEMBL1912605 0.67 EGLN1 (0.63) EGLN1ALDH1A1CYP2D6SMN1; SMN2GAA
SCHEMBL27081099 0.67 ALDH1A1 (0.63) EGLN1ALDH1A1CYP2D6SMN1; SMN2GAA
SCHEMBL16223208 0.67 PPID (0.60) EGLN1ALDH1A1CYP2D6SMN1; SMN2GAA
SCHEMBL1257489 0.66 ALDH1A1 (0.53) ALDH1A1CYP2D6SMN1; SMN2GAAMGAM
SCHEMBL27879862 0.66 ALDH1A1 (0.53) ALDH1A1CYP2D6SMN1; SMN2GAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511818-A Polymer substrates with attached polymer chains 3M创新有限公司 2020-08-07 CN disclosed