Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28439707 | 0.76 | TP53 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28439711 | 0.63 | KDM4E (0.32) | — | |
| SCHEMBL20852284 | 0.62 | AHR (0.34) | METKITFGFR1SRCKDR | |
| SCHEMBL4530542 | 0.62 | ALOX5 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5954140 | 0.58 | MEN1 (0.37) | ALDH1A1 | |
| SCHEMBL5954196 | 0.58 | DRD3 (0.33) | HTTSMN1; SMN2 | |
| SCHEMBL1547567 | 0.58 | L3MBTL1 (0.59) | ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10762036 | 0.56 | L3MBTL1 (0.38) | ALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL7303716 | 0.56 | HIF1A (0.43) | ALDH1A1MAPK1 | |
| SCHEMBL9422903 | 0.56 | HIF1A (0.43) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417396-A | Methods of treating cancer with small molecule NF-kB inhibitors | 免疫目标公司 | 2020-07-14 | — | — | CN | disclosed |