Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451136 | 0.93 | FLT3 (0.55) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28451327 | 0.91 | FLT3 (0.52) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28447004 | 0.91 | SIRT1 (0.52) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28451458 | 0.89 | STK33 (0.49) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28445055 | 0.88 | SIRT1 (0.49) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28451009 | 0.86 | SIRT1 (0.51) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28451471 | 0.86 | MMP2 (0.61) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28450747 | 0.84 | SIRT1 (0.52) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28449289 | 0.84 | MAPT (0.58) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL28451687 | 0.82 | SIRT1 (0.50) | KDM4EMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592529-A | Phenyl pyrazole amide derivative and preparation method and application thereof | 安阳师范学院 | 2020-08-28 | — | — | CN | disclosed |