Methane

Methane

SCHEMBL28443303

C.NC(O)=S.OC(=S)NNc1ccccc1.[NaH]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.48
TSHR P16473 2/20 0.48
TAS2R38 P59533 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TP53 P04637 1/20 0.48
TYR P14679 1/20 0.48
GAA P10253 10/20 0.47
MAPT P10636 6/20 0.47
TDP1 Q9NUW8 4/20 0.46
MAPK1 P28482 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HPGD P15428 1/20 0.46
HIF1A Q16665 1/20 0.46
CYP3A4 P08684 2/20 0.45
ALOX5 P09917 2/20 0.45
CTSD P07339 1/20 0.44
PTGS2 P35354 1/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
NPC1 O15118 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3635635 0.89 GAA (0.55) ALDH1A1TSHRTAS2R38HSD17B10TP53
SCHEMBL163118 0.80 ALDH1A1 (0.61) ALDH1A1TSHRTAS2R38HSD17B10TP53
Methane SCHEMBL11835947 0.80 CTSD (0.48) ALDH1A1GAAMAPTCTSDKDM4E
Methane SCHEMBL9753979 0.78 ALDH1A1 (0.64) ALDH1A1TSHRTAS2R38HSD17B10TP53
Fluoride SCHEMBL31633802 0.78 ALDH1A1 (0.59) ALDH1A1TSHRTAS2R38HSD17B10TP53
SCHEMBL28629293 0.77 ALDH1A1 (0.62) ALDH1A1TSHRTAS2R38HSD17B10TP53
Methyl Alcohol SCHEMBL28274485 0.77 ALDH1A1 (0.61) ALDH1A1TSHRTAS2R38HSD17B10TP53
Methane SCHEMBL1286316 0.76 ALDH1A1 (0.67) ALDH1A1TSHRTAS2R38HSD17B10TP53
Diphenylamine SCHEMBL6483484 0.75 HSD17B10 (0.63) ALDH1A1TSHRTAS2R38HSD17B10TP53
SCHEMBL2885482 0.75 GAA (0.67) ALDH1A1TSHRTAS2R38HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111548292-A Synthesis method and application of heavy metal trapping agent N-methyl-N-phenyl amino sodium dithioformate 青岛中科荣达新材料有限公司 2020-08-18 CN disclosed