Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28443303 | 0.89 | ALDH1A1 (0.48) | GAAMAPTALDH1A1TDP1CTSD | |
| SCHEMBL2885482 | 0.84 | GAA (0.67) | GAAMAPTALDH1A1TDP1CTSD | |
| SCHEMBL163118 | 0.80 | ALDH1A1 (0.61) | GAAMAPTALDH1A1TDP1CTSD | |
| SCHEMBL2231449 | 0.78 | GAA (0.78) | GAAMAPTALDH1A1TDP1CYP3A4 | |
| SCHEMBL11749870 | 0.78 | PTGS2 (0.57) | GAAMAPTALDH1A1TDP1CTSD | |
| Fluoride SCHEMBL31633802 | 0.78 | ALDH1A1 (0.59) | GAAMAPTALDH1A1TDP1CTSD | |
| SCHEMBL28629293 | 0.77 | ALDH1A1 (0.62) | GAAMAPTALDH1A1TDP1CTSD | |
| SCHEMBL10348335 | 0.77 | GAA (0.63) | GAAMAPTALDH1A1TDP1CTSD | |
| SCHEMBL11412488 | 0.77 | GAA (0.58) | GAAMAPTALDH1A1TDP1CTSD | |
| Methyl Alcohol SCHEMBL28274485 | 0.77 | ALDH1A1 (0.61) | GAAMAPTALDH1A1TDP1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160396-A2 | THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS | Agilent Technologies, Inc. (US) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008141248-A2 | THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. (US) | 2008-11-20 | — | — | WO | disclosed |