Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186881 | 0.87 | KDM4E (0.51) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6321532 | 0.83 | ALDH1A1 (0.46) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL17279823 | 0.83 | KDM4E (0.56) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11690868 | 0.81 | ALDH1A1 (0.51) | HTTSMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL10766985 | 0.78 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL6395530 | 0.76 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11125994 | 0.76 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11682761 | 0.76 | KDM4E (0.43) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL28251889 | 0.76 | CYP11B1 (0.53) | NPC1RAB9AMAPTL3MBTL1ADORA2A | |
| SCHEMBL18280811 | 0.76 | KIF11 (0.44) | NPC1RAB9ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794412-B | Preparation method of 4, 5-diaryl-2H-1, 2, 3-triazole compound | 海南师范大学 | 2020-06-30 | — | — | CN | disclosed |