SCHEMBL28444064

SCHEMBL28444064

c1ccc(C[SiH](O[SiH](Cc2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
CALM1 P0DP23 1/20 0.38
IDO1 P14902 3/20 0.36
ALDH1A1 P00352 2/20 0.35
LOXL2 Q9Y4K0 2/20 0.35
TP53 P04637 1/20 0.35
TRPA1 O75762 1/20 0.35
AGXT P21549 1/20 0.34
MAOB P27338 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
CASP1 P29466 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDPK1 O15530 1/20 0.32
MTOR P42345 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
CYP2A6 P11509 1/20 0.32
HTR2A P28223 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3680214 0.73 TP53 (0.36) ALDH1A1TP53ALOX15TAAR1
SCHEMBL28446741 0.72 TSHR (0.43) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL8992224 0.72 CALM1 (0.43) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL8992234 0.72 CALM1 (0.43) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL10824368 0.70 CALM1 (0.36) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL27765573 0.68 SIGMAR1 (0.41) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL9239449 0.68 TP53 (0.42) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL10964825 0.68 TSHR (0.42) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL41196 0.68 CALM1 (0.50) TSHRCALM1IDO1ALDH1A1LOXL2
Hydrochloric Acid SCHEMBL29160220 0.66 CALM1 (0.47) TSHRCALM1IDO1ALDH1A1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed