Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926975 | 0.89 | TP53 (0.32) | TP53KCNH2KCNN4 | |
| SCHEMBL19927509 | 0.89 | TP53 (0.32) | TP53KCNH2KCNN4 | |
| SCHEMBL19927099 | 0.83 | — | — | |
| SCHEMBL6268335 | 0.83 | CA4 (0.35) | TP53KCNH2LTA4HPSIP1CA4 | |
| SCHEMBL630589 | 0.81 | TP53 (0.33) | TP53KCNH2LTA4H | |
| SCHEMBL20006696 | 0.81 | LTA4H (0.34) | TP53KCNH2LTA4H | |
| SCHEMBL705286 | 0.81 | LTA4H (0.34) | TP53KCNH2LTA4HALDH1A1 | |
| SCHEMBL707176 | 0.79 | KCNH2 (0.38) | TP53KCNH2LTA4HCA4LMNA | |
| SCHEMBL706207 | 0.78 | ALDH1A1 (0.32) | TP53MAPK1TAAR1ALDH1A1ALOX15 | |
| SCHEMBL707357 | 0.78 | LMNA (0.37) | TP53LTA4HCES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737291-B2 | 2,4,6,8-tetramethylcyclotetrasiloxane and stabilizer used as a material for thin film formation by chemical vapor deposition, or atomic layer deposition | ADEKA CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20070232821-A1 | Composition Containing Siloxane Compound and Phenol Compound | ADEKA CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232821-A1 | Composition Containing Siloxane Compound and Phenol Compound | H1-0, CYP2S1, H1-4 | TP53 1923/4885KCNH2 1523/4885KCNN4 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.